Scientist examining a sample under a microscope

The Next Standard in Nutra‑Pharmaceutical Therapies

Explore Our Science

Welcome to Exerkine

Founded on Decades of Discovery

  • 18Patents
  • 8Completed Human Studies
  • 11Products Commercially Available

Every feature of aging - fatigue, inflammation, cognitive decline - is the result of mitochondrial dysfunction. At Exerkine, our mission is to restore and protect the body’s power source through scientifically engineered nutra‑pharmaceutical solutions. By targeting energy production at its core, we unlock stronger muscles, sharper cognition, and a healthier, longer life.

Glowing illustration of a DNA double helix on a dark background

Our Science

Research & Technology

Illustration of a mitochondrion

A Research Engine Focused on Cellular Energy

Exerkine’s research engine applies leading expertise in mitochondrial science, exercise physiology, and cellular metabolism to identify compounds that activate the body’s own adaptive pathways. By restoring energy production and cellular performance at the mitochondrial level, our therapies aim to correct the underlying dysfunction driving a wide range of disorders.


Illustration of a cell shown in two halves

Two Domains, One Biological Root

Our programs span both rare genetic disorders and common acquired conditions. Genetic diseases frequently involve mitochondrial or metabolic impairments that are poorly addressed by conventional single-target drugs. Our multi-pathway approach leverages the body’s native biology to deliver broad therapeutic effects while reducing off-target risks. In acquired disorders – those that emerge and accelerate with age – mitochondrial decline drives loss of metabolic efficiency, chronic inflammation, impaired tissue repair, and reduced physiological resilience.


Illustration of cellular structures with a beam of light

Advancing Therapies with Real-World Impact

Across both domains, our R&D pipeline is advancing therapies with the potential to improve strength, cognition, immune function, fertility, metabolic health, and aging-related outcomes. Early studies show meaningful improvements in muscle function, inflammation markers, fat metabolism, and other clinically relevant endpoints. The aim is direct and measurable: restore mitochondrial function so people can live healthier, longer lives.

About Us

Decades of Research, One Vision

  • 570+Peer-Reviewed Publications
  • h‑149Citation Index
  • Featured InTIME, CBC and the Globe and Mail

Dr. Mark Tarnopolsky founded Exerkine to translate decades of human and mechanistic research into a new class of mitochondrial-targeted therapies. Every product we build is rooted in science that has already changed lives.

Meet the Team
Portrait of Dr. Mark Tarnopolsky
Dr. Mark Tarnopolsky Founder, CEO
& Chief Scientific Officer
MD, PhD, FRCP(C)

Our Brand

StayAbove Nutrition

Our flagship consumer brand brings the science of Exerkine to everyday performance. StayAbove Nutrition products are formulated from our core research - built for people who refuse to settle.

Visit StayAboveNutrition.ca StayAbove Nutrition products — Creatine 1, Muscle 5, and Trim 7

Services

What We Offer

View All Services
  • 01

    Nutra-Pharmaceutical Development

    Scientifically engineered formulations targeting foundational drivers of health, grounded in mitochondrial research.

  • 02

    Scientific & Clinical Research

    From concept development through QA to commercialization, supporting informed decisions at every stage.

  • 03

    Regulatory Guidance & Support

    Expert Health Canada and FDA navigation ensuring a compliant, defensible path to market.

  • 04

    Private Label Services

    Scientifically developed formulations and trusted manufacturing capabilities aligned with rigorous quality standards.

  • 05

    Marketing & Creative

    Data-informed positioning and strategic creative that communicates effectively with scientific and consumer audiences.

  • 06

    Product Strategy

    End-to-end guidance on product development, market positioning, and launch planning from formulation to shelf.